A Mutation in the 5′ Untranslated Region Increases Stability of norA mRNA, Encoding a Multidrug Resistance Transporter of Staphylococcus aureus

NorA, a multidrug efflux pump in Staphylococcus aureus, protects the cell from multiple drugs, including quinolones. The flqB mutation (T→G) in the 5′ untranslated region upstream of norA causes norA overexpression of 4.9-fold in cis, as measured in norA::blaZ fusions. The transcriptional initiation...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Fournier, Bénédicte, Truong-Bolduc, Que Chi, Zhang, Xiamei, Hooper, David C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95146/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11244079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.7.2367-2371.2001
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