MeaA, a Putative Coenzyme B(12)-Dependent Mutase, Provides Methylmalonyl Coenzyme A for Monensin Biosynthesis in Streptomyces cinnamonensis

The ratio of the major monensin analogs produced by Streptomyces cinnamonensis is dependent upon the relative levels of the biosynthetic precursors methylmalonyl-coenzyme A (CoA) (monensin A and monensin B) and ethylmalonyl-CoA (monensin A). The meaA gene of this organism was cloned and sequenced an...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Zhang, Weiwen, Reynolds, Kevin A.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2001
Schlagworte:	Physiology and Metabolism
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95104/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11222607/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.6.2071-2080.2001
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