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The miaA Mutator Phenotype of Escherichia coli K-12 Requires Recombination Functions

miaA mutants, which contain A-37 instead of the ms(2)i(6)A-37 hypermodification in their tRNA, show a moderate mutator phenotype leading to increased GC→TA transversion. We show that the miaA mutator phenotype is dependent on recombination functions similar to, but not exactly the same as, those req...

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Udgivet i:J Bacteriol
Principais autores: Zhao, Jingyong, Leung, Hon-Chiu Eastwood, Winkler, Malcolm E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Genetics and Molecular Biology
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC95069/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160115/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.5.1796-1800.2001
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