Drosophila as a Model Host for Pseudomonas aeruginosa Infection

Using the fruit fly Drosophila melanogaster as model host, we have identified mutants of the bacterium Pseudomonas aeruginosa with reduced virulence. Strikingly, all strains strongly impaired in fly killing also lacked twitching motility; most such strains had a mutation in pilGHIJKL chpABCDE, a gen...

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Bibliografiske detaljer
Main Authors: D'Argenio, David A., Gallagher, Larry A., Berg, Celeste A., Manoil, Colin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Physiology and Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC95024/
https://ncbi.nlm.nih.gov/pubmed/11157963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.4.1466-1471.2001
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