Oversynthesis of a New Escherichia coli Small RNA Suppresses Export Toxicity of DsbA′-PhoA Unfoldable Periplasmic Proteins

In Escherichia coli, the DsbA′-PhoA hybrid proteins carrying an unfoldable DsbA′ fragment can be targeted to the envelope, where they exert their toxicity. Hybrid proteins stick to the periplasmic face of the inner membrane and paralyze the export mechanism, becoming lethal if sufficiently overprodu...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Guigueno, Agnès, Dassa, Janie, Belin, Pascal, Boquet, Paul Louis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2001
Assuntos:	Genetics and Molecular Biology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94987/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11157926/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.183.4.1147-1158.2001
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