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In Staphylococcus aureus, Fur Is an Interactive Regulator with PerR, Contributes to Virulence, and Is Necessary for Oxidative Stress Resistance through Positive Regulation of Catalase and Iron Homeostasis

The Staphylococcus aureus genome encodes three ferric uptake repressor (Fur) homologues: Fur, PerR, and Zur. To determine the exact role of Fur in S. aureus, we inactivated the fur gene by allelic replacement using a tetracycline resistance cassette, creating strain MJH010 (fur). The mutant had a gr...

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Detalhes bibliográficos
Main Authors: Horsburgh, Malcolm J., Ingham, Eileen, Foster, Simon J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC94901/
https://ncbi.nlm.nih.gov/pubmed/11133939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.183.2.468-475.2001
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