Transcription Activation by a Variety of AraC/XylS Family Activators Does Not Depend on the Class II-Specific Activation Determinant in the N-Terminal Domain of the RNA Polymerase Alpha Subunit

The N-terminal domain of the RNA polymerase α subunit (α-NTD) was tested for a role in transcription activation by a variety of AraC/XylS family members. Based on substitutions at residues 162 to 165 and an extensive genetic screen we conclude that α-NTD is not an activation target for these activat...

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Main Authors: Egan, Susan M., Pease, Andrew J., Lang, Jeffrey, Li, Xiang, Rao, Vydehi, Gillette, William K., Ruiz, Raquel, Ramos, Juan L., Wolf, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2000
Assuntos:
Genetics and Molecular Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC94837/
https://ncbi.nlm.nih.gov/pubmed/11092872
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