Spore Photoproduct (SP) Lyase from Bacillus subtilis Specifically Binds to and Cleaves SP (5-Thyminyl-5,6-Dihydrothymine) but Not Cyclobutane Pyrimidine Dimers in UV-Irradiated DNA

The predominant photolesion in the DNA of UV-irradiated dormant bacterial spores is the thymine dimer 5-thyminyl-5,6-dihydrothymine, commonly referred to as spore photoproduct (SP). A major determinant of SP repair during spore germination is its direct reversal by the enzyme SP lyase, encoded by th...

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Библиографические подробности
Главные авторы: Slieman, Tony A., Rebeil, Roberto, Nicholson, Wayne L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2000
Предметы:
Genetics and Molecular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC94787/
https://ncbi.nlm.nih.gov/pubmed/11053385
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