Spore Photoproduct (SP) Lyase from Bacillus subtilis Specifically Binds to and Cleaves SP (5-Thyminyl-5,6-Dihydrothymine) but Not Cyclobutane Pyrimidine Dimers in UV-Irradiated DNA

The predominant photolesion in the DNA of UV-irradiated dormant bacterial spores is the thymine dimer 5-thyminyl-5,6-dihydrothymine, commonly referred to as spore photoproduct (SP). A major determinant of SP repair during spore germination is its direct reversal by the enzyme SP lyase, encoded by th...

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הוצא לאור ב:	J Bacteriol
Principais autores:	Slieman, Tony A., Rebeil, Roberto, Nicholson, Wayne L.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Genetics and Molecular Biology
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11053385/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.22.6412-6417.2000
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