Silencing and Activation of ClyA Cytotoxin Expression in Escherichia coli

Cytolysin A (ClyA) is a pore-forming cytotoxic protein encoded by the clyA gene of Escherichia coli K-12. Genetic analysis suggested that clyA is silenced by the nucleoid protein H-NS. Purified H-NS protein showed preferential binding to clyA sequences in the promoter region, as evidenced by DNase I...

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Hlavní autoři: Westermark, Marie, Oscarsson, Jan, Mizunoe, Yoshimitsu, Urbonaviciene, Jurate, Uhlin, Bernt Eric
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Genetics and Molecular Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC94780/
https://ncbi.nlm.nih.gov/pubmed/11053378
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