The Amino Terminus of Pseudomonas aeruginosa Outer Membrane Protein OprF Forms Channels in Lipid Bilayer Membranes: Correlation with a Three-Dimensional Model

Pseudomonas aeruginosa OprF forms 0.36-nS channels and, rarely, 2- to 5-nS channels in lipid bilayer membranes. We show that a protein comprising only the N-terminal 162-amino-acid domain of OprF formed the smaller, but not the larger, channels in lipid bilayers. Circular dichroism spectroscopy indi...

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Pubblicato in:	J Bacteriol
Autori principali:	Brinkman, Fiona S. L., Bains, Manjeet, Hancock, Robert E. W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2000
Soggetti:	Cell Surfaces
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94676/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10960112/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.18.5251-5255.2000
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