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Lesions in gshA (Encoding γ-l-Glutamyl-l-Cysteine Synthetase) Prevent Aerobic Synthesis of Thiamine in Salmonella enterica Serovar Typhimurium LT2

Thiamine pyrophosphate is an essential cofactor that is synthesized de novo in Salmonella enterica serovar Typhimurium and other bacteria. In addition to genes encoding enzymes in the biosynthetic pathway, mutations in other metabolic loci have been shown to prevent thiamine synthesis. The latter lo...

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Bibliografiska uppgifter
Huvudupphovsmän: Gralnick, Jeffrey, Webb, Eric, Beck, Brian, Downs, Diana
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC94667/
https://ncbi.nlm.nih.gov/pubmed/10960103
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