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Genetic Characterization of Escherichia coli Type 1 Pilus Adhesin Mutants and Identification of a Novel Binding Phenotype

Five Escherichia coli type 1 pilus mutants that had point mutations in fimH, the gene encoding the type 1 pilus adhesin FimH, were characterized. FimH is a minor component of type 1 pili that is required for the pili to bind and agglutinate guinea pig erythrocytes in a mannose-inhibitable manner. Po...

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Published in:J Bacteriol
Main Authors: Hamrick, Terri S., Harris, Sandra L., Spears, Patricia A., Havell, Edward A., Horton, John R., Russell, Perry W., Orndorff, Paul E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2000
Subjects:
Cell Surfaces
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94587/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10869080/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.14.4012-4021.2000
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