Metabolic Defects Caused by Mutations in the isc Gene Cluster in Salmonella enterica Serovar Typhimurium: Implications for Thiamine Synthesis

The metabolic consequences of two insertions, iscR1::MudJ and iscA2::MudJ, in the isc gene cluster of Salmonella enterica serovar Typhimurium were studied. Each of these insertions had polar effects and caused a nutritional requirement for the thiazole moiety of thiamine. Data showed that IscS was r...

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Detalhes bibliográficos

Publicado no:	J Bacteriol
Principais autores:	Skovran, Elizabeth, Downs, Diana M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Physiology and Metabolism
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94571/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10869064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.14.3896-3903.2000
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