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Tol1, a Fission Yeast Phosphomonoesterase, Is an In Vivo Target of Lithium, and Its Deletion Leads to Sulfite Auxotrophy

Lithium is the drug of choice for the treatment of bipolar affective disorder. The identification of an in vivo target of lithium in fission yeast as a model organism may help in the understanding of lithium therapy. For this purpose, we have isolated genes whose overexpression improved cell growth...

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Udgivet i:J Bacteriol
Principais autores: Miyamoto, Rumi, Sugiura, Reiko, Kamitani, Shinya, Yada, Tomoko, Lu, Yabin, Sio, Susie O., Asakura, Masahiro, Matsuhisa, Akio, Shuntoh, Hisato, Kuno, Takayoshi
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2000
Fag:
Eukaryotic Cells
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94529/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10850973/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.13.3619-3625.2000
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