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Analysis of Escherichia coli RecA Interactions with LexA, λ CI, and UmuD by Site-Directed Mutagenesis of recA

An early event in the induction of the SOS system of Escherichia coli is RecA-mediated cleavage of the LexA repressor. RecA acts indirectly as a coprotease to stimulate repressor self-cleavage, presumably by forming a complex with LexA. How complex formation leads to cleavage is not known. As an app...

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Detalhes bibliográficos
Main Authors: Mustard, Julie A., Little, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC94464/
https://ncbi.nlm.nih.gov/pubmed/10692372
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