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Geranylgeranyltransferase I of Candida albicans: Null Mutants or Enzyme Inhibitors Produce Unexpected Phenotypes

Geranylgeranyltransferase I (GGTase I) catalyzes the transfer of a prenyl group from geranylgeranyl diphosphate to the carboxy-terminal cysteine of proteins with a motif referred to as a CaaX box (C, cysteine; a, usually aliphatic amino acid; X, usually L). The α and β subunits of GGTase I from Sacc...

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Sparad:
I publikationen:J Bacteriol
Huvudupphov: Kelly, Rosemarie, Card, Deborah, Register, Elizabeth, Mazur, Paul, Kelly, Theresa, Tanaka, Ken-Ichi, Onishi, Janet, Williamson, Joanne M., Fan, Hongxia, Satoh, Toshihiko, Kurtz, Myra
Materialtyp: Artigo
Språk:Inglês
Utgiven: American Society for Microbiology (ASM) 2000
Ämnen:
Eukaryotic Cells
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10633104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.182.3.704-713.2000
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