Copper/Zinc-Superoxide Dismutase Is Required for Oxytetracycline Resistance of Saccharomyces cerevisiae

Saccharomyces cerevisiae, along with other eukaryotes, is resistant to tetracyclines. We found that deletion of SOD1 (encoding Cu/Zn superoxide dismutase) rendered S. cerevisiae hypersensitive to oxytetracycline (OTC): a sod1Δ mutant exhibited a >95% reduction in colony-forming ability at an OTC...

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Bibliografske podrobnosti
Main Authors: Avery, Simon V., Malkapuram, Srividya, Mateus, Carolina, Babb, Kimberly S.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Eukaryotic Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC94242/
https://ncbi.nlm.nih.gov/pubmed/10613865
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