Regulated Antisense RNA Eliminates Alpha-Toxin Virulence in Staphylococcus aureus Infection

The ability to selectively disrupt gene function remains a critical element in elucidating information regarding gene essentiality for bacterial growth and/or pathogenesis. In this study, we adapted a tet regulatory expression system for use in Staphylococcus aureus, with the goal of downregulating...

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Bibliografische Detailangaben

Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Ji, Yinduo, Marra, Andrea, Rosenberg, Martin, Woodnutt, Gary
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1999
Schlagworte:	Genetics and Molecular Biology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC94120/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10542157/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.21.6585-6590.1999
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