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Toxicity of Copper, Cobalt, and Nickel Salts Is Dependent on Histidine Metabolism in the Yeast Saccharomyces cerevisiae

The pH-dependent inhibition of 22 metal salts have been systematically investigated for the yeast Saccharomyces cerevisiae. We have established that the inhibition of growth by Cu, Co, or Ni salts is markedly enhanced by histidine auxotrophy and by increasing the pH of the medium. Each of the his1-h...

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Autori principali: Pearce, David A., Sherman, Fred
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC93961/
https://ncbi.nlm.nih.gov/pubmed/10438744
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