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Growth Phase-Dependent Regulation of Vsr Endonuclease May Contribute to 5-Methylcytosine Mutational Hot Spots in Escherichia coli

Using rabbit polyclonal antibodies, we have shown that the Dcm cytosine methylase of Escherichia coli is maintained at a constant level during cell growth, while Vsr endonuclease levels are growth phase dependent. Decreased production of Vsr relative to Dcm during the log phase may contribute substa...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Macintyre, Georgina, Pitsikas, Photini, Cupples, Claire G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93950/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10400606/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.14.4435-4436.1999
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