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Increased rrn Gene Dosage Causes Intermittent Transcription of rRNA in Escherichia coli

When the number of rRNA (rrn) operons in an Escherichia coli cells is increased by adding an rrn operon on a multicopy plasmid, the rate of rRNA expression per operon is reduced to maintain a constant concentration of rRNA in the cell. We have used electron microscopy to examine rRNA transcription i...

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Detalhes bibliográficos
Main Authors: Voulgaris, Justina, French, Sarah, Gourse, Richard L., Squires, Craig, Squires, Catherine L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC93916/
https://ncbi.nlm.nih.gov/pubmed/10400572
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