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An Intracellular Iron Chelator Pleiotropically Suppresses Enzymatic and Growth Defects of Superoxide Dismutase-Deficient Escherichia coli

Mutants of Escherichia coli that lack cytoplasmic superoxide dismutase (SOD) exhibit auxotrophies for sulfur-containing, branched-chain, and aromatic amino acids and cannot catabolize nonfermentable carbon sources. A secondary-site mutation substantially relieved all of these growth defects. The req...

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Библиографические подробности
Главные авторы: Maringanti, Sujatha, Imlay, James A.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC93858/
https://ncbi.nlm.nih.gov/pubmed/10368155
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