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Bacteriophage T4 rnh (RNase H) Null Mutations: Effects on Spontaneous Mutation and Epistatic Interaction with rII Mutations

The bacteriophage T4 rnh gene encodes T4 RNase H, a relative of a family of flap endonucleases. T4 rnh null mutations reduce burst sizes, increase sensitivity to DNA damage, and increase the frequency of acriflavin resistance (Ac(r)) mutations. Because mutations in the related Saccharomyces cerevisi...

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Bibliografiska uppgifter
Huvudupphovsmän: Bebenek, Anna, Smith, Leslie A., Drake, John W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC93767/
https://ncbi.nlm.nih.gov/pubmed/10322013
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