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Histidine Operon Deattenuation in dnaA Mutants of Salmonella typhimurium Correlates with a Decrease in the Gene Dosage Ratio between tRNA(His) and Histidine Biosynthetic Loci

Expression of the histidine operon of Salmonella typhimurium is increased in dnaA(Ts) mutants at 37°C. This effect requires an intact his attenuator and can be suppressed by increasing the gene copy number of the hisR locus, which encodes the tRNA(His). We present data which suggest that the his dea...

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Détails bibliographiques
Auteurs principaux: Blanc-Potard, Anne-Beatrice, Figueroa-Bossi, Nara, Bossi, Lionello
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC93740/
https://ncbi.nlm.nih.gov/pubmed/10217789
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