Escherichia coli Outer Membrane Protein TolC Is Involved in Production of the Peptide Antibiotic Microcin J25

A Tn5 insertion in tolC eliminated microcin J25 production. The mutation had little effect on the expression of the microcin structural gene and presumably acted by blocking microcin secretion. The tolC mutants carrying multiple copies of the microcin genes were less immune to the microcin. TolC is...

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Pubblicato in:	J Bacteriol
Autori principali:	Delgado, Mónica A., Solbiati, José O., Chiuchiolo, María J., Farías, Ricardo N., Salomón, Raúl A.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1999
Soggetti:	Physiology and Metabolism
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC93605/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10074099/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.181.6.1968-1970.1999
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