Effect of ppGpp on Escherichia coli Cyclopropane Fatty Acid Synthesis Is Mediated through the RpoS Sigma Factor (ς(S))

Strains of Escherichia coli carrying mutations at the relA locus are deficient in cyclopropane fatty acid (CFA) synthesis, a phospholipid modification that occurs as cultures enter stationary phase. RelA protein catalyzes the synthesis of guanosine-3′,5′-bisdiphosphate (ppGpp); therefore, ppGpp was...

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Bibliographic Details
Main Authors: Eichel, Johannes, Chang, Ying-Ying, Riesenberg, Dieter, Cronan, John E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC93412/
https://ncbi.nlm.nih.gov/pubmed/9882672
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