Engineering Cytochrome P450 BM-3 for Oxidation of Polycyclic Aromatic Hydrocarbons

Cytochrome P450 BM-3, a self-sufficient P450 enzyme from Bacillus megaterium that catalyzes the subterminal hydroxylation of long-chain fatty acids, has been engineered into a catalyst for the oxidation of polycyclic aromatic hydrocarbons. The activities of a triplet mutant (A74G/F87V/L188Q) towards...

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Autors principals: Li, Qing-Shan, Ogawa, Jun, Schmid, Rolf D., Shimizu, Sakayu
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Enzymology and Protein Engineering
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC93367/
https://ncbi.nlm.nih.gov/pubmed/11722930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.12.5735-5739.2001
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