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Evidence for the Biosynthesis of Bryostatins by the Bacterial Symbiont “Candidatus Endobugula sertula” of the Bryozoan Bugula neritina

The marine bryozoan, Bugula neritina, is the source of the bryostatins, a family of macrocyclic lactones with anticancer activity. Bryostatins have long been suspected to be bacterial products. B. neritina harbors the uncultivated gamma proteobacterial symbiont “Candidatus Endobugula sertula.” In th...

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Autors principals: Davidson, S. K., Allen, S. W., Lim, G. E., Anderson, C. M., Haygood, M. G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC93199/
https://ncbi.nlm.nih.gov/pubmed/11571152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.10.4531-4537.2001
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