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Reduction in Exopolysaccharide Viscosity as an Aid to Bacteriophage Penetration through Pseudomonas aeruginosa Biofilms

To cause an infection, bacteriophages must penetrate the alginate exopolysaccharide of Pseudomonas aeruginosa to reach the bacterial surface. Despite a lack of intrinsic motility, phage were shown to diffuse through alginate gels at alginate concentrations up to 8% (wt/vol) and to bring about a 2-lo...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Principais autores: Hanlon, Geoffrey W., Denyer, Stephen P., Olliff, Cedric J., Ibrahim, Lamia J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC92934/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11375190/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.67.6.2746-2753.2001
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