Applications of Gene Replacement Technology to Streptomyces clavuligerus Strain Development for Clavulanic Acid Production

Cephamycin C production was blocked in wild-type cultures of the clavulanic acid-producing organism Streptomyces clavuligerus by targeted disruption of the gene (lat) encoding lysine ɛ-aminotransferase. Specific production of clavulanic acid increased in the lat mutants derived from the wild-type st...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Paradkar, A. S., Mosher, R. H., Anders, C., Griffin, A., Griffin, J., Hughes, C., Greaves, P., Barton, B., Jensen, S. E.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Genetics and Molecular Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC92869/
https://ncbi.nlm.nih.gov/pubmed/11319114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.67.5.2292-2297.2001
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы