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A Protein Disulfide Isomerase Gene Fusion Expression System That Increases the Extracellular Productivity of Bacillus brevis

We have developed a versatile Bacillus brevis expression and secretion system based on the use of fungal protein disulfide isomerase (PDI) as a gene fusion partner. Fusion with PDI increased the extracellular production of heterologous proteins (light chain of immunoglobulin G, 8-fold; geranylgerany...

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Detalhes bibliográficos
Main Authors: Kajino, Tsutomu, Ohto, Chikara, Muramatsu, Masayoshi, Obata, Shusei, Udaka, Shigezo, Yamada, Yukio, Takahashi, Haruo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC91874/
https://ncbi.nlm.nih.gov/pubmed/10653729
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