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Inducible Amplification of Gene Copy Number and Heterologous Protein Production in the Yeast Kluyveromyces lactis

Heterologous protein production can be doubled by increasing the copy number of the corresponding heterologous gene. We constructed a host-vector system in the yeast Kluyveromyces lactis that was able to induce copy number amplification of pKD1 plasmid-based vectors upon expression of an integrated...

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書誌詳細
主要な著者: Morlino, Giovanni B., Tizzani, Lorenza, Fleer, Reinhard, Frontali, Laura, Bianchi, Michele M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1999
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC91648/
https://ncbi.nlm.nih.gov/pubmed/10543790
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