Quantitative PCR Assay To Measure Aspergillus fumigatus Burden in a Murine Model of Disseminated Aspergillosis: Demonstration of Efficacy of Caspofungin Acetate

Caspofungin acetate (MK-0991) is an antifungal antibiotic that inhibits the synthesis of 1,3-β-d-glucan, an essential component of the cell wall of several pathogenic fungi. Caspofungin acetate was recently approved for the treatment of invasive aspergillosis in patients who are refractory to or int...

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Detalhes bibliográficos
Main Authors: Bowman, J. C., Abruzzo, G. K., Anderson, J. W., Flattery, A. M., Gill, C. J., Pikounis, V. B., Schmatz, D. M., Liberator, P. A., Douglas, C. M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Analytical Procedures
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90856/
https://ncbi.nlm.nih.gov/pubmed/11709327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.12.3474-3481.2001
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