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Rifampin Resistance in Mycobacterium kansasii Is Associated with rpoB Mutations

Rifampin is the most potent drug used in the treatment of disease due to Mycobacterium kansasii. A 69-bp fragment of rpoB, the gene that encodes the β subunit of the bacterial RNA polymerase, was sequenced and found to be identical in five rifampin-susceptible clinical isolates of M. kansasii. This...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Klein, John L., Brown, Timothy J., French, Gary L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90781/
https://ncbi.nlm.nih.gov/pubmed/11600355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.11.3056-3058.2001
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