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DPC 681 and DPC 684: Potent, Selective Inhibitors of Human Immunodeficiency Virus Protease Active against Clinically Relevant Mutant Variants

Human immunodeficiency virus (HIV) protease inhibitors (PIs) are important components of many highly active antiretroviral therapy regimens. However, development of phenotypic and/or genotypic resistance can occur, including cross-resistance to other PIs. Development of resistance takes place becaus...

Deskribapen osoa

Gorde:
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Kaltenbach, Robert F., Trainor, George, Getman, Daniel, Harris, Greg, Garber, Sena, Cordova, Beverly, Bacheler, Lee, Jeffrey, Susan, Logue, Kelly, Cawood, Pamela, Klabe, Ronald, Diamond, Sharon, Davies, Marc, Saye, Joanne, Jona, Janan, Erickson-Viitanen, Susan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology (ASM) 2001
Gaiak:
Antiviral Agents
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90777/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11600351/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.11.3021-3028.2001
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