Two New Point Mutations at A2062 Associated with Resistance to 16-Membered Macrolide Antibiotics in Mutant Strains of Mycoplasma hominis

We describe two mutants of Mycoplasma hominis PG-21 which show resistance to 16-membered macrolides but susceptibility to lincosamides, obtained by in vitro exposure to increasing doses of josamycin. The 23S rRNA gene showed that each had a mutation (A2062G and A2062T) corresponding to nucleotide 20...

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Detalhes bibliográficos
Main Authors: Furneri, Pio Maria, Rappazzo, Giancarlo, Musumarra, Maria Pia, Di Pietro, Patrizia, Catania, Lucrezia S., Roccasalva, Lucia Silvana
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Mechanisms of Resistance
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90764/
https://ncbi.nlm.nih.gov/pubmed/11557502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2958-2960.2001
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