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Effects of New Quinolones on Transepithelial Electrical Potential Difference of Tracheal Mucosa In Vivo

Superfusion of canine tracheal mucosa with 100 μg each of grepafloxacin and ciprofloxacin per ml reduced the electrical transepithelial potential difference in vivo by more than 50%. This effect was dose dependent, specific for new quinolones, and inhibited by Cl channel blockers, indicating that ne...

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Detalhes bibliográficos
Main Authors: Kanoh, Soichiro, Tamaoki, Jun, Kondo, Mitsuko, Nagano, Yuko, Nagai, Atsushi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90755/
https://ncbi.nlm.nih.gov/pubmed/11557493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2928-2930.2001
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