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Pharmacodynamics of Gemifloxacin against Streptococcus pneumoniae in an In Vitro Pharmacokinetic Model of Infection

The pharmacodynamics of gemifloxacin against Streptococcus pneumoniae were investigated in a dilutional pharmacodynamic model of infection. Dose fractionation was used to simulate concentrations of gemifloxacin in human serum associated with 640 mg every 48 h (one dose), 320 mg every 24 h (two doses...

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Published in:Antimicrob Agents Chemother
Main Authors: MacGowan, Alasdair P., Rogers, Chris A., Holt, H. Alan, Wootton, Mandy, Bowker, Karen E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2001
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90752/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557490/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2916-2921.2001
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