Animal Pharmacokinetics and Interspecies Scaling of Sordarin Derivatives following Intravenous Administration

Sordarin derivatives constitute a new group of synthetic antifungal agents that selectively inhibit fungal protein synthesis. They have demonstrated in vitro activity against the most important fungal pathogens, both yeast and filamentous. This new family of compounds has also shown in vivo activity...

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Main Authors: Aviles, P., Pateman, A., San Roman, R., Guillén, M. J., Gómez De Las Heras, F., Gargallo-Viola, D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2001
Ábhair:
Pharmacology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC90732/
https://ncbi.nlm.nih.gov/pubmed/11557470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.10.2787-2792.2001
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