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Antiviral Efficacy and Pharmacokinetics of Oral Adefovir Dipivoxil in Chronically Woodchuck Hepatitis Virus-Infected Woodchucks

The antiviral efficacy of orally administered adefovir dipivoxil was evaluated in an 18-week study (12 weeks of treatment and 6 weeks of recovery) conducted with woodchucks chronically infected with woodchuck hepatitis virus (WHV). Adefovir dipivoxil is a prodrug of adefovir designed to enhance its...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Cullen, John M., Li, Daniel H., Brown, Cynthia, Eisenberg, Eugene J., Cundy, Kenneth C., Wolfe, Julie, Toole, Jay, Gibbs, Craig
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11557463/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.10.2740-2745.2001
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