Novel Cefotaximase (CTX-M-16) with Increased Catalytic Efficiency Due to Substitution Asp-240→Gly

Three clinical strains (Escherichia coli Rio-6, E. coli Rio-7, and Enterobacter cloacae Rio-9) collected in 1996 and 1999 from hospitals in Rio de Janeiro (Brazil) were resistant to broad-spectrum cephalosporins and gave a positive double-disk synergy test. Two bla(CTX-M) genes encoding β-lactamases...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bonnet, R., Dutour, C., Sampaio, J. L. M., Chanal, C., Sirot, D., Labia, R., De Champs, C., Sirot, J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90641/
https://ncbi.nlm.nih.gov/pubmed/11451684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.8.2269-2275.2001
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