In Vitro Activity of Gemifloxacin (SB-265805, LB20304a) against Legionella pneumophila and Its Pharmacokinetics in Guinea Pigs with L. pneumophila Pneumonia

The activity of gemifloxacin against intracellular Legionella pneumophila and for the treatment of guinea pigs with L. pneumophila pneumonia was studied. Gemifloxacin, azithromycin, and levofloxacin (1 μg/ml) reduced bacterial counts of two L. pneumophila strains grown in guinea pig alveolar macroph...

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Bibliographic Details
Main Authors: Edelstein, Paul H., Shinzato, Takashi, Doyle, Edward, Edelstein, Martha A. C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90632/
https://ncbi.nlm.nih.gov/pubmed/11451675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.8.2204-2209.2001
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