Novel Mutations in ndh in Isoniazid-Resistant Mycobacterium tuberculosis Isolates

Novel mutations in NADH dehydrogenase (ndh) were detected in 8 of 84 (9.5%) isoniazid (INH)-resistant isolates (T110A [n = 1], R268H [n = 7]), but not in 22 INH-susceptible isolates of Mycobacterium tuberculosis. Significantly, all eight isolates with mutations at ndh did not have mutations at katG,...

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Bibliographic Details
Main Authors: Lee, Ann S. G., Teo, Audrey S. M., Wong, Sin-Yew
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC90621/
https://ncbi.nlm.nih.gov/pubmed/11408244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2157-2159.2001
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