Fluoroquinolone Resistance in Anaerobic Bacteria following Exposure to Levofloxacin, Trovafloxacin, and Sparfloxacin in an In Vitro Pharmacodynamic Model

This investigation explored pharmacodynamic characteristics of fluoroquinolones against Bacteroides thetaiotamicron and the potential for development of resistance. An in vitro model was used to generate kill curves with three fluoroquinolones at various area under the concentration-time curve (AUC)...

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Autores principales: Ross, Gigi H., Wright, David H., Hovde, Laurie Baeker, Peterson, Marnie L., Rotschafer, John C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC90615/
https://ncbi.nlm.nih.gov/pubmed/11408238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.7.2136-2140.2001
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