Azithromycin Inhibits Quorum Sensing in Pseudomonas aeruginosa

We report that 2 μg of azithromycin/ml inhibits the quorum-sensing circuitry of Pseudomonas aeruginosa strain PAO1. Addition of synthetic autoinducers partially restored the expression of the trancriptional activator-encoding genes lasR and rhlR but not that of the autoinducer synthase-encoding gene...

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Bibliografiske detaljer
Main Authors: Tateda, Kazuhiro, Comte, Rachel, Pechere, Jean-Claude, Köhler, Thilo, Yamaguchi, Keizo, Van Delden, Christian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
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Mechanisms of Action: Physiological Effects
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC90577/
https://ncbi.nlm.nih.gov/pubmed/11353657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.6.1930-1933.2001
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