Azithromycin Inhibits Quorum Sensing in Pseudomonas aeruginosa

We report that 2 μg of azithromycin/ml inhibits the quorum-sensing circuitry of Pseudomonas aeruginosa strain PAO1. Addition of synthetic autoinducers partially restored the expression of the trancriptional activator-encoding genes lasR and rhlR but not that of the autoinducer synthase-encoding gene...

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Podrobná bibliografie

Vydáno v:	Antimicrob Agents Chemother
Hlavní autoři:	Tateda, Kazuhiro, Comte, Rachel, Pechere, Jean-Claude, Köhler, Thilo, Yamaguchi, Keizo, Van Delden, Christian
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2001
Témata:	Mechanisms of Action: Physiological Effects
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90577/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353657/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.6.1930-1933.2001
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