In Vitro Activities of DU-1102, a New Trioxaquine Derivative, against Plasmodium falciparum Isolates

The antimalarial trioxaquine derivative DU-1102, synthesized by covalent linkage between aminoquinoline and trioxane moieties, was highly active against Cameroonian isolates (mean 50% inhibitory concentration of 43 nmol/liter) of Plasmodium falciparum. There was no correlation between the responses...

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Autores principales: Basco, Leonardo K., Dechy-Cabaret, Odile, Ndounga, Mathieu, Meche, Fleurette Solange, Robert, Anne, Meunier, Bernard
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Susceptibility
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC90564/
https://ncbi.nlm.nih.gov/pubmed/11353644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.6.1886-1888.2001
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