Atovaquone Nanosuspensions Show Excellent Therapeutic Effect in a New Murine Model of Reactivated Toxoplasmosis

Immunocompromised patients are at risk of developing toxoplasma encephalitis (TE). Standard therapy regimens (including sulfadiazine plus pyrimethamine) are hampered by severe side effects. While atovaquone has potent in vitro activity against Toxoplasma gondii, it is poorly absorbed after oral admi...

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發表在:	Antimicrob Agents Chemother
Principais autores:	Schöler, Nadja, Krause, Karsten, Kayser, Oliver, Müller, Rainer H., Borner, Klaus, Hahn, Helmut, Liesenfeld, Oliver
格式:	Artigo
語言:	Inglês
出版:	American Society for Microbiology (ASM) 2001
主題:	Experimental Therapeutics
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.45.6.1771-1779.2001
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