Thermoreversible Gel Formulations Containing Sodium Lauryl Sulfate or n-Lauroylsarcosine as Potential Topical Microbicides against Sexually Transmitted Diseases

The microbicidal efficacies of two anionic surfactants, sodium lauryl sulfate (SLS) and n-lauroylsarcosine (LS), were evaluated in cultured cells and in a murine model of herpes simplex type 2 (HSV-2) intravaginal infection. In vitro studies showed that SLS and LS were potent inhibitors of the infec...

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Autors principals: Roy, Sylvie, Gourde, Pierrette, Piret, Jocelyne, Désormeaux, André, Lamontagne, Julie, Haineault, Caroline, Omar, Rabeea F., Bergeron, Michel G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC90530/
https://ncbi.nlm.nih.gov/pubmed/11353610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.6.1671-1681.2001
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