Pharmacokinetics of Itraconazole Oral Solution in Neutropenic Children during Long-Term Prophylaxis

We investigated the pharmacokinetics and safety of an oral solution of itraconazole in two groups of neutropenic children stratified by age. Effective concentrations of itraconazole in plasma were reached quickly and maintained throughout treatment. The results indicate a trend toward higher concent...

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Detalhes bibliográficos
Main Authors: Schmitt, Claudine, Perel, Yves, Harousseau, Jean-luc, Lemerle, Sophie, Chwetzoff, Elisabeth, le Moing, Jean-Pierre, Levron, Jean-Claude
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC90507/
https://ncbi.nlm.nih.gov/pubmed/11302829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.45.5.1561-1564.2001
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